Dear Colleagues,

T21RS aims to establish an exciting scientific program for the 2021 T21RS International Conference (June 9-12, 2022 Long Beach, California, USA) with a broad range of topics. The Scientific Program Committee invites you to contribute by submitting a proposal for a symposium in basic, clinical and/or translational research in Down syndrome.

We encourage both established and junior investigators to contribute to the program of the meeting. We welcome symposium ideas from preclinical and clinical science areas, ranging from molecular biology to human research, and especially topics that bridge scientific disciplines. We will prioritize symposium ideas that may combine clinical/behavioral/basic science/mouse models centered on a theme, with less of a focus on an approach per se (see examples below – note you are not limited to these themes).  We also look forward to evaluating proposals that include people new to the Down syndrome research space to promote collaborations and foster new investigators.

We encourage you to help us make the 2021 T21RS meeting in Long Beach a success! Proposals will be accepted only from T21RS members.  If you are not a T21RS member, please join at


Instructions for symposium proposals

Please include:

  1. A descriptive symposium title
  2. A short outline describing the topic and its relevance to the field (max. 2000 characters with spaces, about 250 words).
  3. Three lecture titles and associated speaker information (with one back-up speaker).

This is an international meeting and we value a diverse pool of speakers, so please consider speakers from various countries. Gender balance is also important. Preference will be given to proposals that include at least one presentation from a junior investigator. Formal approval from the proposed speakers is not yet necessary. Symposia that make connections between clinical, behavioral and basic science or include the combination of multidisciplinary approaches around a common theme, are warmly invited. Symposium organizers will have the opportunity to select an extra short talk from a young investigator, from a list of selected oral communications provided by the Program Committee.

Thank you on behalf of the Scientific Program Committee,

Theme 1 Genomic and epigenetic mechanisms
Genetics, genomics, epigenetics, other -omics

Theme 2 Molecular and Cellular Mechanisms
Mitochondria, metabolism, Inflammation, immunity, autoimmunity

Theme 3 Experimental models
Phenotyping, animal models, cellular models, stem cells and reprogramming

Theme 4 Cognition and Behavior
Human and animal studies on cognition, intellectual disability, neuropsychology, language, behaviour

Theme 5 Neurodegeneration
Alzheimer’s disease in Down syndrome

Theme 6 Neurodevelopment
Neuropathology, neurogenesis, cell proliferation, synaptogenesis, nervous system patterning

Theme 6 Co-occurring Illnesses
Cancer/ Leukemia, Psychiatric Disorders, Metabolic disorders, Sensory Disorders, Cardiovascular Diseases, other

Theme 7 Therapeutic intervention
Pharmacological/non-pharmacological interventions, neurotherapy, preclinical and clinical

Theme 8 Evaluation
Biomarkers, neuroimaging, outcome measures

Theme 8 Other

Important announcement

The in-person meeting of T21RS for 2021
has been postponed to 2022
We are moving to a Virtual Meeting in 2021

(more info on the Home page)

T21 RS Committee